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La Clinique du Sommeil
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Clinical study

A preliminary study on sleep apnea and buprenorphine

A preliminary study examined the association between chronic buprenorphine use and sleep-related breathing disorders. Cases of central sleep apnea were observed, raising concerns about the respiratory safety of patients using this medication.

A preliminary study on sleep apnea and buprenorphine

Study background

Buprenorphine is an opioid medication that, unlike other opioids, has an improved respiratory safety profile. However, deaths have been reported among buprenorphine users, raising questions about its impact on breathing during sleep.

Observed results

The study examined 11 patients using buprenorphine chronically. Four of these patients exhibited central sleep apnea, with a significant apnea index. Patients with central sleep apnea had lower oxygen saturation levels compared to those without significant apnea.

Implications for patients

These results suggest that chronic buprenorphine use may be linked to sleep-related breathing disorders, similar to those observed with other opioids. Patients using this medication should be aware of the potential risks to their breathing during sleep.

This article is provided for information only and does not replace medical advice. For any question about your own situation, talk to your doctor.